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It may have motivated George Whipple, who had a keen interest in liver diseases, to investigate the liver's role in hematopoiesis

It is found in animal-based foods such as meat, fish, eggs, and dairy products

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Neelakantan and colleagues (Biochem Pharmacol, 2017) then took the pharmacological step, reporting that selective, membrane-permeable small-molecule NNMT inhibitors reversed high-fat-diet-induced obesity in mice this is the study most directly relevant to the 5-Amino-1MQ class, because it moves from the target matters to a drug against the target does something in a live animal. And again, it is a mouse study