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Genetic variants in the MUT gene, causing MMA, can be divided into two types: (Mut-), a partial genetic variant in the MUT gene that results in low to moderate residual MUT activity in the presence of high concentrations of Adenosylcobalamin (AdoCbl), and (Mut0), a complete genetic variant in the MUT gene resulting in virtually undetectable MUT activity [12]

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The company's regulatory consulting capabilities span FDA, EMA, PMDA, and Health Canada submissions, with a particular focus on helping organizations without dedicated regulatory affairs infrastructure design DCT protocols that satisfy the specific consent, data integrity, and remote monitoring requirements of their target submission jurisdictions

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