Glutathione deficiency may promote cancer initiation (by failing to protect DNA from oxidative damage), while elevated glutathione in established tumors may promote cancer progression and treatment resistance (by protecting cancer cells from chemotherapy and radiation) [2][5]
[DOI] [PMC free article] [PubMed] [Google Scholar] 100.Pospil P., Prasad A., Rc M
Some research from Germany has shown that an even higher threshold (over 500 pg/mL) is necessary in early-to-mid pregnancy to maintain vitamin B12 levels throughout pregnancy, lactation, and to support an infants vitamin B12 status (via breast milk) through 6 months of age
doi: 10.1002/1531-8249(200004)47:4 3.0.CO;2-5
7d, e, phosphorylated STAT3-S727 (p-STAT3-S727), but not STAT3-Y705 (p-STAT3-Y705), significantly increased in TC1-6 cells after high-level glutamine and alanine administration