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doi: 10.3389/fnut.2022.853846 Received 13 January 2022 Accepted 14 February 2022 Published 04 April 2022 Volume 9 - 2022 Edited by Minhao Xie, Nanjing University of Finance and Economics, China Reviewed by Lanting Zeng, South China Botanical Garden (CAS), China

Redondo and Morris, 2011) provides an attractive framework

In a different study done n the Indian population with Melasma consisting of 312 patients, the female to male ratio was much lower, i.e., 4:1

Copper is particularly relevant given its role in collagen cross-linking, which is partly why GHK-Cu (a copper-carrying peptide) is relevant to tissue repair

Cancer 71 : 15711580 Reed E (1998) Platinum-DNA adduct, nucleotide excision repair and platinum based anti- cancer chemotherapy