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This feature of DFO makes it a selective chelating agent for iron and aluminium, and following chelation, it results in molecules of ferrioxamine and aluminoxamine, respectively being formed

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However, MT-2 is not FDA approved, and long-term safety data is limited

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These findings demonstrate that Gipr Syn/ mice are resistant to the weight-lowering effects of mGIPR-Ab, highlighting the crucial role of CNS GIPR for the body weight response to mGIPR-Ab

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Given that genetically defined neurons in the NTS like those that express CCK and the CalcR suppress food intake via separate pathways, it is possible that their combined activation has an additive effect, which proved to be the case [82]

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J Biol Chem 226:497509 Friedwald WT, Levy RI, Fredrickson DS (1972) Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without the use of the preparative ultracentrifuge

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