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Pharmacological Approaches Anti-spasmodics, including dicyclomine, hyoscyamine, and hyoscine, may reduce abdominal pain by relaxing intestinal smooth muscle, but can worsen constipation and lack strong evidence for IBS-C pain relief [104, 105]
Other supplements that have been proposed to help include vitamin C, zinc, curcumin (from turmeric), bromelain, collagen and glucosamine
Rolling circle amplification reaction An isothermal DNA or RNA amplification reaction where circular oligonucleotides (for example, C-circles) function as a template for the DNA or RNA polymerase
[70] The situation in mammals is even less clear