*Correspondence: Gabriela Halitchi, [email protected] Singeap, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
This conversion directly supports mitochondrial bioenergetics, leading to higher adenosine triphosphate (ATP) levels in hepatocytes (liver cells) and preventing the mitochondrial dysfunction that often accompanies severe toxic burden
The GSH:GSSG ratio is a widely used biomarker of cellular oxidative stress, with depletion implicated in neurodegeneration, hepatic injury, and immune dysfunction
One key player in this intricate dance is glutathione, a potent antioxidant found within every cell
12 However, recent studies have shown that GST also takes part in promoting multidrug resistance in p53-mutated lung cancer cells