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GPX4 catalyzes the reduction of hydrogen peroxide, organic hydroperoxides, and lipid peroxides at the expense of reduced glutathione and functions in the protection of cells against oxidative stress

Well over 100 different mutations have been documented in cystinosis [8, 9]

Fatty acid synthase, an enzyme that acts in an NADPH-dependent manner, catalyzes the synthesis of fatty acids, such as palmitate, a key product in the composition of membrane phospholipids, in protein acylation, and as a precursor in cholesterol synthesis [58]

injections of 100 nmol kg 1 MK-801 ( n = 12 rats), 100 nmol kg 1 GLP-1 ( n = 12 rats), 100 nmol kg 1 GLP-1MK-801 ( n = 12 rats) or vehicle (isotonic saline, n = 13 rats) for three consecutive days while being offered the voluntary choice between chow and kaolin (a non-food product)

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