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Patients frequently describe a profound, crushing fatigue that does not improve with rest, accompanied by a thick, disorienting cognitive impairment commonly referred to as "brain fog." For those living with these invisible illnesses, the frustration of navigating a medical system that often lacks clear answers can be just as exhausting as the physical symptoms themselves

Plain sterile water is acceptable only for single-use experiments because there is no preservative for the multi-week draw window

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