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Of note, mitochondrial impairment occurs early in PD pathogenesis, especially at the level of complex I, and animal models of PD are generated after administration of complex I inhibitors such as 1-methyl-4-phenylpyridinium (MPP+) [104]

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Int Immunopharmacol 147:113967

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10.1016/j.siny.2004.03.001

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In diabetic nephropathy models, VDR activation alleviates lipid peroxidation by modulating ATP citrate lyase (ACLY) and the Nrf2/Keap1 axis (29)

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It supports the hormonal environment that helps training and nutrition work more effectively

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