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Gallo et al., 2014a

Prostate, pancreatic, and kidney cancers showed no statistically significant difference

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BDNF supports the survival and function of sensory and motor neurons, and its deficiency contributes to nerve degeneration

There are no approved therapies for youth that have demonstrated a clinically meaningful impact on body weight or BMI reduction compared with placebo. Hannon said the 2025 American Diabetes Association Standards of Care currently recommend GLP-1 therapy if children and adolescents with type 2 diabetes are unable to achieve an HbA1c of 6.5% or less with metformin or insulin therapy