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Patients taking semaglutide were also at numerically reduced risk for nonfatal MI (HR 0.72 [95% CI 0.610.85]) and nonfatal stroke (HR 0.93 [95% CI 0.741.15]) relative to patients receiving placebo, though these endpoints were not adjusted for multiplicity and shall not infer definitive treatment effects [18]

Bottom line Some Ozempic users report that starting the medication has impacted their menstrual cycles

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