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ROS production is associated with cancer development, atherosclerosis, diabetes, inflammation, aging, and other harmful processes

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Supplementing with vitamin B12 may be important for vegetarians, vegans, and older adults who may not absorb nutrients as easily

-Addisons disease and other endocrine disorders Addisons disease, is characterized by deficient production of hormones of the adrenal cortex, leading to increased production of adrenocorticotropic hormone (ACTH) (32)