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Antioxidants inhibit the human cortical neuron apoptosis induced by hydrogen peroxide, tumor necrosis factor alpha, dopamine and beta-amyloid peptide 1-42

The implication of GST polymorphisms may be significant as studies suggest that that loss of mu, pi and theta GST genes increase susceptibility to inflammatory diseases, and a genetic deficiency of GSTM1 is associated with increased susceptibility to ozone-related asthma [61] and to susceptibility to AFB1-mediated damage to human liver cells [62]

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Sena LA, Chandel NS (2012) Physiological roles of mitochondrial reactive oxygen species

This backs customizing treatment plans to the individual