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These effects were dose-dependent and required the copper complex (GHK without copper showed minimal effects)

Figure 7 shows the assessment of targeting of the plasma component conjugated nanoparticles, which showed significantly higher cellular uptake and displayed better targeting efficacy than alginate conjugated nanoparticles, with a higher fluorescence intensity in brain tumor cells and tissues after 3 -24 h, while reaching maximum at 12 h

10.1046/j.1471-4159.1996.66041448.x 50