Differential regulation of cyclooxygenase-2 and inducible nitric oxide synthase by 4-hydroxynonenal in human osteoarthritic chondrocytes through ATF-2/CREB-1 transactivation and concomitant inhibition of NF-kappaB signaling cascade
4.1.1 Cell proliferation and differentiation By Tsukagoshi et al., ROS homeostasis regulates the primary phase of tissue differentiation, which is marked by the transformation from proliferation to cellular elongation [54, 55], as they observed the differential distribution of O 2 and H 2 O 2 in the root tissue of model plant Arabidopsis
Induction of autophagy by spermidine promotes longevity
CD44(+) cells have cancer stem cell-like properties in nasopharyngeal carcinoma
Moreover, in a mouse model of ovarian clear cell carcinoma lacking the ARID1A gene, the efficacy of combination therapy comprising HDAC6 inhibitors and anti-PD-L1 antibody has been successfully demonstrated (147, 148).Reducing the generation of ROS could potentially aid in the prevention of the malignant progression of endometriosis (149)
