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The investigator-led phase 2 LixiPark trial of lixisenatide looked at the progression of motor symptoms in 156 people living with Parkinsons whose symptoms had been stabilised using standard antiparkinsonian drugs

Creatine supplementation, when combined with resistance training, may increase lean mass and muscle strength

Promoting energy balance: GLP-1 helps the body decide when to store or use energy

The net effect is therefore best treated as an empirical question, not a settled mechanismconsistent with the comparative observational findings summarised below

Effect of Subcutaneous Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy on Body Weight in Adults With Overweight or Obesity: The STEP 3 Randomized Clinical Trial