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Vincent et al., 1999)

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Suggestive but not conclusive evidence preclinical studies, small clinical trials, and anecdotal reports has found that GLP-1 agonists might improve memory, reduce rates of dementia, and more, suggesting they may be effective Alzheimers treatments

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Signaling via pancreatic -cells underlies the insulinotropic effects of GLP-1 RAs, while activation of enteric GLP-1Rs delays gastric emptying, effectively blunting postprandial glucose spikes and prolonging satiety (Kreymann et al., 1987