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Glucose is transported into intestinal L-cells by sodium-glucose cotransporters, and the resultant increase in Ca 2+ influx triggers GLP-1 secretion 32

Patients discuss any history of mood disorders, anxiety, or psychiatric medication use with their clinical team

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Multiple NIH institutes, including NIAAA and NIDA, have invested tens of millions in clinical trials studying GLP-1 receptor agonists for substance use disorders, including alcohol addiction

Semaglutide works by mimicking the effects of the naturally occurring hormone GLP-1, which plays a pivotal role in regulating appetite and food intake