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A 2016 meta-analysis found insufficient evidence for oral glutathione

It makes an untested freeze-dried powder in a vial sound like a proven drug

Comorbid MDD (PTSD + MDD) did not affect GSH in the ACC ( p = 0.623, n = 23 PTSD, n = 7 PTSD+MDD), nor in the DLPFC ( p = 0.457, n = 9 PTSD, n = 5 PTSD + MDD)

Primary hippocampal neuron cultures are used to study Dihexa's proposed effects on dendritic spine density and synaptic protein expression, typically measuring morphological changes via fluorescence microscopy and quantifying synaptic marker expression (such as PSD-95 or synaptophysin) relative to untreated controls

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