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Emerging cross-kingdom evidence indicates that redox-regulated mitochondrial proteostasis and calcium-dependent stress signalling modules identified in plant systems can inform mechanistic hypotheses in mammalian neurodegeneration

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Zhang Y, Xi X, Mei Y, Zhao X, Zhou L, Ma M, et al

Which Interventions Reduce Side Effects in Practice The evidence points consistently in one direction: most GI side effects are manageable, and how they are managed determines whether patients stay on treatment long enough to benefit