Some patients may start with an ODT because they are hesitant about injections and later switch to a weekly injection for stronger or simpler treatment
Molecular and biochemical mechanisms mainly included the increased oxidative stress through polyol pathway flux, the accumulation of advanced glycation end products, the hexosamine pathway, and the protein kinase C pathway
Stay Hydrated: Gastrointestinal side effects, particularly diarrhea, can lead to dehydration
Anna Yoder, DNP, FNP-C, is a board-certified family nurse practitioner and founder of Telehealth NP
Metformin: Co-administration of multiple twice-daily doses of sitagliptin with metformin, an OCT substrate, did not meaningfully alter the pharmacokinetics of metformin in patients with type 2 diabetes