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Emerging evidence suggests that tryptophan metabolism may be an important regulator of many of these processes

Indeed, L-Carnitine (-hydroxy--trimethylaminobutyrate), a quaternary amine, is known as a natural antioxidant found in mammals

The SDHB encoded protein contains three distinct Fe-S (iron-sulfur) centers that facilitate the transfer of electrons from FADH 2 to ubiquinone (coenzyme Q: CoQ)

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This organ distribution difference enables the brain, kidneys and small intestines to sequester GSH from the blood circulation to meet the need of these organs for GSH, and provide a solid foundation for developing organ selective agents for these organs in general