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However, there are IGF-I receptors on the nonparenchymal cells[89, 90] and it has been reported that IGF-I stimulates both DNA synthesis[91, 92] and the production of hepatocyte growth factor (HGF) in hepatic stellate cells in vitro [87]

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The mass tolerances for precursor ions and fragment ions were set at 4.5 ppm and 0.05 Da, respectively