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Many pharmaceutical companies have tried to develop drugs that target Mcl-1, but this has been difficult because the interaction between Mcl-1 and its target protein occurs in a long stretch of 20 to 25 amino acids, which is difficult to block with the small molecules typically used as drugs

Generative AI statement The authors declare that no Gen AI was used in the creation of this manuscript

Some researchers apply copper peptide solutions after microneedling sessions, reasoning that the enhanced penetration through treatment channels delivers peptide directly to the dermal layer

Methylcobalamin at the doses used (100 mcg) is extremely well tolerated and rarely causes adverse effects on its own

As a result, binding efficiency may be reduced at low expression levels, leading to low recovery of the fusion protein