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They also found that the conjugate has distinct effects on the activity and protein expression of the hypothalamus, a brain region that regulates satiety and is key to the effects of GLP-1 drugs

The depressor axis of the renin-angiotensin system and brain disorders: a translational approach

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Extending from this observation, one may speculate that multi-chimeras along the lines of the one we discovered could get us closer to the bariatric surgery standard of lasting weight loss. Reference: Molecular Design of Unimolecular Tetra-Receptor Agonists by Tristan C