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Here, we demonstrate that dihexa binds with high affinity to hepatocyte growth factor (HGF) and both dihexa and its parent compound Norleucine 1-AngIV (Nle1- AngIV) induce c-Met phosphorylation in the presence of subthreshold concentrations of HGF and augment HGF- dependent cell scattering

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However, this approach does not measure GR activity directly but rather infers it indirectly based on the rate at which oxidized glutathione is reduced to its reduced form

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Vagianos 2007