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Differential gene expression between Zucker Fatty rats ad Zucker Diabetic Fatty rats: A potential role for the immediate-early gene Egr-1 in regulation of beta cell proliferation

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MR analysis focusing on drug pathways, known as 'Drug target MR', has been a widely adopted method for examining the causal effects of these pathways on disease endpoints [27]

However, the translational potential of these agents is hampered by the lack of rigorous clinical validation, standardization, and mechanistic clarity

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