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These pathways are often overactive in individuals with ulcerative colitis , Crohns disease , and other inflammatory bowel disorders

It also releases pro-inflammatory cytokine and induces hypoxia and fibrosis but with fewer immune cells and a higher proportion of small adipocytes, leading to a healthier adipose tissue phenotype (Choe et al., 2016)

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Enhancing inhibitory synaptic function reverses spatial memory deficits in Shank2 mutant mice

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