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In further asepcts, the invention provides methods of reversing, ameliorating or slowing progression of at least one symptom of Lewy body pathology in a patient in need thereof

It was suggested that by increasing leucine intake, more leptin will be secreted, suppressing food intake, which leads to weight loss, improved insulin sensitivity and decreases in blood pressure

It is also a co-factor for GPX4-mediated lipid detoxification 35 , and GPX4 activity is necessary for the survival of several tissues, including the liver 36 and kidney 37