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The kidneys then filter water-soluble compounds, xenobiotic metabolites, and protein breakdown products from the bloodstream and move them into urine for elimination

Mutations in CFTR result in decreased fluid secretions and an increased fluid reabsorption leading to mucus dehydration [31]

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Generation of HeLa cells stably expressing APEX2 For generation of stable cell lines, the pLPCX retroviral expression vector encoding APEX2-GFP or mito-APEX2 (Su9-APEX2) was transfected into the packaging cell line Phoenix-AMPHO

Porter et al, 2018