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Furthermore, glutamine can change the composition or function of microbiota [78] by potentially influencing gut microbial metabolism, including the production of the metabolites from the tumor-promoting/suppressing gut microbiome, metabolites that contribute to extracellular acidosis, and short-chain fatty acids (SCFAs) that provide energy to colonic epithelial cells [85,86,87,88]

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At the 4-week mark, the first dose increase typically occurs (from 0.25 mg to 0.5 mg on Ozempic/Wegovy), which can temporarily restart GI symptoms

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