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Funding Research in the Mandal Laboratory is supported by grants from the National Institute of Health (1 R15 HL170257-01) and the Schwartzberg Companies

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Mice were anesthetized with Zoletil 50 (75 mg/kg, intraperitoneal injection [i.p.]) and xylazine (10 mg/kg, i.p.), and their body temperature was maintained at 37 C using a thermostatic electric blanket

Science has shown us that poor sleep quality can impact weight regulation through its effects on appetite-regulating hormones

If combined GI symptoms become severe or persistent, notify your prescribing provider immediatelythey may adjust timing protocols, reduce doxycycline dose frequency, or recommend short-term anti-nausea medications to bridge the adjustment period