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192 Studies have shown that Fusobacterium nucleatum promotes the occurrence and development of UC by destroying the normal intestinal structure, downregulating the level of tight junction proteins, promoting the apoptosis of intestinal epithelial cells, increasing the expression of inflammatory cytokines, and disrupting the balance of the intestinal microbiota

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Based on an analysis of 68 RCTs encompassing 60,720 participants, Shihab et al