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Protein, essential fatty acids, vitamins, and minerals all become harder to consume in adequate amounts

Discovery of a novel inhibitor of NAD(P)(+)-dependent malic enzyme (ME2) by high-throughput screening

Serum creatinine is a common indicator used to evaluate kidney function

What This Means Practically For patients with Type 2 diabetes, these findings have practical implications: First-line treatment recommendation: Major diabetes guidelines now recommend GLP-1 agonists as first-line treatment (alongside or instead of metformin) for patients with established cardiovascular disease

Wegovy should not be used in patients with a history of severe allergic reactions to Semaglutide or in patients with a personal or family history of medullary thyroid carcinoma or a rare condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)