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During public comment, Nina Zeldes of Public Citizen's Health Research Group said the substance's supposed benefits are " largely based on anecdotal evidence" and that interest in it " appears to be driven by those who stand to benefit from increased demand

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The peptide is a modified fragment of the growth hormone where the last 16 amino acids (176-191) have been reproduced as a specific peptide, called GH Fragment 176-191 or simply AOD 9604

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Allergic reactions are possible, though infrequent