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10.1371/journal.pone.0065205 53 GarretnV.CarpinelliJ.JordanaX.HoluigueL

* A New Approach to Weight Management Why controlling hormonal hunger signals is more effective than willpower alone

- India as a global pricing anchor As seen in APIs and vaccines, India could once again reset global reference pricing for obesity and diabetes drugs -Margin compression vs volume expansion The value pool is shiftingfrom per-unit profitability to patient scale Competitive differentiation evolves -Future moats will likely depend on: Clinical outcomes & next-gen formulations Delivery innovation (oral GLP-1, long-acting injectables) Integrated care ecosystems

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