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COVID-19 and the Hypothalamus Pituitary Adrenal (HPA) Axis The HPA axis is a neuroendocrine component that integrates the hypothalamus, pituitary, and adrenal glands, working through a complex positive and negative feedback system depending on hormones and receptors in these three organs, modulating multiple physiological and pathological processes

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Nucleic Acids Res, 2012