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It has been shown using various atherosclerosis animal models that GLP-1RA therapy is associated with a reduction in atherosclerotic plaques, prevention of aorta intima-media thickening, improvement in vascular endothelial function, reduction of the necrotic zone and an increase of the fibrous component in the plaque and plaque stabilisation

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However, further cohort studies with larger sample sizes are needed to confirm the associations found in the present study

Cortisol is a steroid hormone made by the adrenal glands that plays a critical role in the response to stress