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Harms, G

It is FDA-approved and shown to be a more effective option for some people than single-receptor GLP-1 medications like Semaglutide

For example, in certain embodiments, a sustained and/or extended release formulation described herein comprises a combination of poloxamer 407 (pluronic F127) and carboxymethylcellulose (CMC) in a ratio of about 40:1, about 35:1, about 30:1, about 25:1, about 20:1, about 15:1, about 10:1, or about 5:1.4%, about 4.5%, or about 5% of the total weight of the formulation or composition

furosemide) can increase urinary excretion of thiamine and thereby lower B levels over time

When combined with DAC (Drug Affinity Complex), it extends the half-life, making it more stable and longer-lasting