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Las PARPs consumen NAD+ durante los procesos de reparacin del ADN, y el dao crnico del ADN que se acumula con la edad agota progresivamente las reservas celulares de NAD+
Researchers have found that only around 40% of people are able to produce urolithin A due to differences in individual gut microbiomes.6 Fortunately, other studies have found that the remaining 60% of people can overcome that limitation through supplementation.12 Most of the potential benefits of urolithin A are attributed to the compounds effects on mitophagy.7 This is when your body cleans up damaged or excess mitochondria,8 then replaces them with new, healthy ones to maintain mitochondrial homeostasis.14 As you age, the rate and effectiveness of the mitophagy process decrease
European Journal of Endocrinology , 139 (5), 552561
Under the leadership of Dr
Half-life Not established in humans no published human pharmacokinetic study exists
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