surmount-1 tirzepatide obesity nejm 2022 weight loss percent for maintenance of bodyweight reduction in people with in the USA (SURMOUNT-MAINTAIN): a multicentre, double-blind, randomised, placebo-controlled trial GLP-1 Medications for Weight Loss:

In summary, GLP-1s aren't just drugs

However, researchers found a slightly higher incidence of psychiatric adverse events in the Contrave group compared to placebo

The ratio of serum ALT to ALP, both expressed as multiples of the upper limit of normal (ULN) were used to define the type of hepatic injury, with ratios of 5 for hepatocellular pattern liver injury

(PubMed) McCleery J, Abraham RP, Denton DA, et al

While individual requirements vary based on factors like age, sex, activity level, and health status, most adults need a minimum of 1,200 calories daily for women and 1,500 for men to obtain adequate protein, vitamins, and minerals