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These real-life experiences underline the commonality of bloating as a side effect

However, as discussed in that rule, we continue to disagree that all hospitals can produce a payer-specific negotiated charge in dollars that meets the definition of a standard charge because hospitals establish payer-specific negotiated charges in many ways, ranging from basic fee schedules (in which dollar amounts for specific items and services are known), to grouper methodologies (in which a base rate in dollars has been established but may then be modified depending on other factors like transfers or outliers), to percent of billed charges schemes (in which the dollar amount varies from person to person)

By week 72, 88% of participants were able to maintain their target dose

Across the full SURMOUNT clinical program (SURMOUNT-1 through -4), GI side effects of any kind affected 27.8% to 72.8% of tirzepatide participants depending on dose and indication, with discontinuation due to GI symptoms running 110.5%

Monitoring blood glucose levels (where appropriate) helps identify patterns that may contribute to fatigue