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Codon optimised sequences of NAPstar3b and HyPer7 for expression in mammalian cells were commercially synthesised (Supplementary Table 4) (GenScript Biotech, Rijswijk, Netherlands) and delivered in pcDNA3.1(+) plasmids

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Immunocompromised individuals or those on systemic retinoids may experience additive dryness and should initiate treatment with the Sensitive strength only under close monitoring