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These medications work by mimicking the incretin hormone GLP-1, enhancing glucose-dependent insulin secretion, suppressing glucagon release, slowing gastric emptying, and reducing appetite through central nervous system pathways

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It targets a specific region of the brain responsible for regulating appetite and food consumption

GLP-1s are built to act like a hormone your body already makesone that helps you feel full after eating, keeps hunger at bay and slows digestion enough to avoid energy crashes

Yet for a minority, the opposite can occur, and understanding the why helps guide solutions