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In addition, some studies have found significantly higher levels of thiobarbituric acid reactive substances (TBARS, a marker of lipid peroxidation) as well as malondialdehyde (MDA, a marker of cellular oxidative damage) in the urine of patients with kidney stones [56, 57]

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Cinchonine induces apoptosis of HeLa and A549 cells through targeting TRAF6

Moreover, studies were also included that combined caffeine and other bioactive compounds found in coffee, green tea, other beverages, food, and medicine