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[5] proved that GIP, originally named gastric inhibitory polypeptide, could explain this incretin effect by inducing glucose-stimulated insulin secretion, and renamed the peptide as glucose-dependent insulinotropic polypeptide. Following the identification of GIP, the search for insulinotropic incretins persevered

A systematic review published in Frontiers in Endocrinology examined GLP-1 agonist and SGLT2 inhibitor use during pregnancy and lactation in animal models

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In this study, there were two patients with this coagulation disorder, while the prevalence in the general population is only 1:5000 50