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This approach, originally proposed by Professor Ernest Starling in the early 1900s, initially focused on gut hormones but was overshadowed by discoveries in insulin and leptin [14]
Not as potent as medication While certain foods and dietary strategies can increase GLP-1 naturally, the magnitude is far less than what is achievable with medications
GCs reduce peripheral glucose uptake, promote apoptosis in -cells and increase -cell glucagon production, collectively exacerbating hyperglycaemia (69)
The agency has identified some areas of concern for compounded GLP-1 drugs
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