Each pen delivers an exact amount of medication, starting at 2.5 mg weekly and potentially increasing to 15 mg weekly based on patient response
Participants had lived with diabetes for around 2.5 years when the trial began, and had not taken any medications to treat their condition for at least 90 days
Secondary outcomes were analyzed on an ITT basis using linear regression, adjusted for baseline weight, type of surgery, sex, diabetes status and the baseline value of the corresponding outcome
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The extra copy of the APP gene that patients with DS have is implicated in their increased risk for acquiring early-onset AD
