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"Obesity, like many other chronic diseases, is a progressive, relapsing disease, which may require long-term treatment," Jaisinghani says a framing now codified in the World Health Organization's first global GLP-1 guideline, issued in December 2025, which conditionally recommends these therapies as part of a comprehensive obesity treatment approach

Vitamin D works closely with calcium and magnesium

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This is possible thanks to a supply of probiotics that maintains the balance of the microbiota